Anti-CD40 Anticorps (A323725)

Name: Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free
Brand: Antibodies.com
SKU: A323725
Price: 295.0 USD
Availability: InStock

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$295

Anticorps monoclonal de Human contre CD40 pour ELISA, FACS, Functional Assay et In Vivo.

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Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 7-10 jours ouvrables.

Nous ContacterContact

Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

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Mots clés :

Anticorps Recombinant Microglia Marker Plasma Membrane Marker

Spécifications

Nom du produit

Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free

Description du produit

Recombinant human monoclonal antibody to CD40.

Applications

ELISA, FACS, Functional Assay, In Vivo

Reactivité

Human, Cynomolgus Macaque

Hôte

Human

Clonalité

Monoclonal

Isotype

IgG2SA - Human IgG2 with S387A mutation

Chaînes légères

kappa

Conjuguer

Unconjugated

Purification

Protein A affinity chromatography.

Concentration

Reconstitution dependent.

Masse moléculaire

This antibody has a predicted MW of 146.2 kDa.

Pureté

> 95% (by SDS-PAGE and SEC-HPLC).

Forme du produit

Lyophilized

Reconstitution

Reconstitute with 100µl of sterile double-distilled water to bring antibody to 1mg/ml concentration. Gently shake to solubilize completely. Do not vortex!

Formulation

Lyophilized from 25mM Histadine, pH 6.2, with 8% Sucrose and 0.01% Tween80.

Stockage

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Synonymes

AI326936, B cell associated molecule , B cell associated molecule CD40, B cell surface antigen CD40 , B cell-associated molecule, B-cell surface antigen CD40, Bp50, CD 40 , CD40 antigen , CD40 antigen (TNF receptor superfamily member 5), CD40 molecule , CD40 molecule TNF receptor superfamily member 5, CD40 molecule, TNF receptor superfamily member 5, CD40 protein , CD40 type II isoform , CD40L receptor , CDw40, GP39 , HIGM1, IGM , IMD3, MGC9013, Nerve growth factor receptor related B lymphocyte activation molecule , NFRSF5 , OTTHUMP00000031699, OTTHUMP00000031700 , p50, T BAM , T-BAM, TBAM, TNF receptor superfamily member 5, TNFRSF5, TNR5_HUMAN, TRAP, Tumor necrosis factor receptor superfamily , member 5, Tumor necrosis factor receptor superfamily member 5, Tumor necrosis factor receptor superfamily member 5 precursor , Tumor necrosis factor receptor superfamily, member 5, isoform CRA_a

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (7)

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Figure 1: SDS-PAGE - Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free (A323725)

SDS-PAGE analysis of Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free (A323725) under reducing (R) conditions confirms that the purity of this antibody is greater than 95%.

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Figure 2: Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free (A323725)

SEC-HPLC analysis of Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free (A323725) confirms that the purity of this antibody is greater than 95%.

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Figure 3: Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free (A323725)

Immobilized recombinant human CD40 protein (His tag) at 2 µg/ml is bound by Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free (A323725). EC₅₀ = 0.009782 µg/ml.

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Figure 4: Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free (A323725)

Selicrelumab Biosimilar - Anti-CD40 Antibody - Low endotoxin, Azide free (A323725) inhibited the tumor growth of MC38 on Humanized CD40 mice. The result showed significant anti-tumor effects.