Recombinant Anti-SOX11 Anticorps [SOX11/3235R] (A250020)

Anticorps monoclonal [SOX11/3235R] de lapin contre SOX11 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-SOX11 Antibody [SOX11/3235R]
Description du produit
Recombinant rabbit monoclonal [SOX11/3235R] antibody to SOX11.
Spécificité
This antibody recognizes a protein of ~47kDa, identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker for identifying true cyclin D1-negative MCL.
Applications
IHC-P
Recommander des dilutions
IHC-P: 2-4 µg/ml
Reactivité
Human
Immunogène
Recombinant fragment, around amino acids 300-400, of human SOX11 protein. The exact sequence is proprietary.
Hôte
Rabbit
Clonalité
Monoclonal
Clone
SOX11/3235R
Isotype
IgG
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
47 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-SOX11 Antibody [SOX11/3235R] - BSA and Azide free (A253200).
Synonymes
MRD27, SOX11_HUMAN, SRY (sex determining region Y) box 11, SRY related HMG box gene 11, SRY-box 11, Transcription factor SOX-11
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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