Anti-SOX2 Anticorps [SOX2/1791] (A250002)

Name: Anti-SOX2 Antibody [SOX2/1791]
Brand: Antibodies.com
SKU: A250002
Price: 525.0 USD
Availability: InStock

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$525

Anticorps monoclonal [SOX2/1791] de souris contre SOX2 pour ELISA, WB et IHC-P.

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Garantie de Correspondance des Prix

Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

Nous ContacterContact

Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Mots clés :

Anticorps Monospécifique iPSCs Marker Neural Stem Cell Marker Neuroepithelial Marker Radial Glia Marker

Spécifications

Nom du produit

Anti-SOX2 Antibody [SOX2/1791]

Description du produit

Mouse monoclonal [SOX2/1791] antibody to SOX2.

Spécificité

SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

Applications

ELISA, WB, IHC-P

Recommander des dilutions

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Reactivité

Human, Mouse

Immunogène

Recombinant fragment, within amino acids 176-305, of human SOX2 protein. The exact sequence is proprietary.

Hôte

Mouse

Clonalité

Monoclonal

Clone

SOX2/1791

Isotype

IgG2b

Chaînes légères

kappa

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Masse moléculaire

34 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-SOX2 Antibody [SOX2/1791] - BSA and Azide free (A253182).

Synonymes

ANOP3, cb236, Delta EF2a, lcc, MCOPS3, MGC148683, MGC2413, RGD1565646, Sex determining region Y box 2, SOX 2, SOX2_HUMAN, SRY (sex determining region Y) box 2, SRY box containing gene 2, SRY related HMG box 2, SRY related HMG box gene 2, SRY-box 2, Transcription factor SOX 2, Transcription factor SOX-2, ysb

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (9)

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Figure 1: Immunohistochemistry - Anti-SOX2 Antibody [SOX2/1791] (A250002)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cervical carcinoma using Anti-SOX2 Antibody [SOX2/1791].

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Figure 2: Western Blot - Anti-SOX2 Antibody [SOX2/1791] (A250002)

Western blot analysis of recombinant SOX2 protein fragment and NCCIT cell lysate using Anti-SOX2 Antibody [SOX2/1791].

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Figure 3: Immunohistochemistry - Anti-SOX2 Antibody [SOX2/1791] (A250002)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human lung carcinoma using Anti-SOX2 Antibody [SOX2/1791].

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Figure 4: Immunohistochemistry - Anti-SOX2 Antibody [SOX2/1791] (A250002)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded mouse stomach using Anti-SOX2 Antibody [SOX2/1791].

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Figure 5: Immunohistochemistry - Anti-SOX2 Antibody [SOX2/1791] (A250002)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded mouse brain using Anti-SOX2 Antibody [SOX2/1791].

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Figure 6: Immunohistochemistry - Anti-SOX2 Antibody [SOX2/1791] (A250002)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded mouse intestine using Anti-SOX2 Antibody [SOX2/1791].

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Figure 7: SDS-PAGE - Anti-SOX2 Antibody [SOX2/1791] (A250002)

SDS-PAGE analysis of Anti-SOX2 Antibody [SOX2/1791] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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Figure 8: Western Blot - Anti-SOX2 Antibody [SOX2/1791] (A250002)

Western blot analysis of human A549 cell lysate using Anti-SOX2 Antibody [SOX2/1791].

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Figure 9: Anti-SOX2 Antibody [SOX2/1791] (A250002)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-SOX2 Antibody [SOX2/1791]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

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