Anti-SOX4 Anticorps [SOX4/2540] (A250008)

Anticorps monoclonal [SOX4/2540] de souris contre SOX4 pour IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-SOX4 Antibody [SOX4/2540]
Description du produit
Mouse monoclonal [SOX4/2540] antibody to SOX4.
Spécificité
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF--induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival invitro and for primary tumor growth and metastasis invivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.
Applications
IHC-P
Recommander des dilutions
IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human SOX4 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
SOX4/2540
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
47 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-SOX4 Antibody [SOX4/2540] - BSA and Azide free (A253188).
Synonymes
Ecotropic viral integration site 16, EVI 16, EVI16, SOX4_HUMAN, SRY (sex determining region Y) box 4, SRY box containing gene 4, SRY related HMG box gene 4, Transcription factor SOX-4
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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