Anti-SPARC Anticorps [OSTN/3758] (A277807)

Name: Anti-SPARC Antibody [OSTN/3758]
Brand: Antibodies.com
SKU: A277807
Price: 525.0 USD
Availability: InStock

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$525

Anticorps monoclonal [OSTN/3758] de souris contre SPARC pour WB et IHC-P.

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Alternative Formats and ConjugatesAlternative Formats

Carrier Free and Preservative Free

Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 4-6 jours ouvrables.

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Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

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Mots clés :

Anticorps Monospécifique

Spécifications

Nom du produit

Anti-SPARC Antibody [OSTN/3758]

Description du produit

Mouse monoclonal [OSTN/3758] antibody to SPARC.

Spécificité

SPARC (for secreted protein acidic and rich in cysteine) is a phosphorylated, acidic, glycine-rich glycoprotein that is secreted by endothelial cells and is present in large amounts in the parietal endoderm of mouse embryos and in human placenta. It is identical to osteonectin, a protein important to bone calcification that is highly conserved between species. SPARC, which can be selectively expressed by the endothelium in response to certain types of injury, induces rounding in adherent endothelial cells in vitro. It regulates endothelial barrier function through F-Actin-dependent changes in cell shape, coincident with the appearance of intercellular gaps, which provide a paracellular pathway for extravasation of macromolecules.

Applications

WB, IHC-P

Recommander des dilutions

WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml

Reactivité

Human

Immunogène

Recombinant fragment, around amino acids 1-200, of human SPARC protein. The exact sequence is proprietary.

Hôte

Mouse

Clonalité

Monoclonal

Clone

OSTN/3758

Isotype

IgG1

Chaînes légères

kappa

Conjuguer

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Masse moléculaire

38 kDa

Forme du produit

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Stockage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes générales

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-SPARC Antibody [OSTN/3758] - BSA and Azide free (A278395).

Synonymes

AA517111, Basement membrane protein 40, Basement-membrane protein 40, BM 40, BM-40, BM40, Cysteine rich protein, hm:zeh0062, MGC128090, OI17, ON, Osteonectin, Secreted acidic cystein rich glycoprotein, Secreted protein acidic and cysteine rich, Secreted protein acidic and rich in cysteine, Secreted protein acidic cysteine rich, Secreted protein acidic cysteine rich (osteonectin), SPRC, SPRC_HUMAN

Contrôles isotype

Anticorps secondaires appropriés

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (4)

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Figure 1: Western Blot - Anti-SPARC Antibody [OSTN/3758] (A277807)

Western blot analysis of JEG-3 cell line lysate using Anti-SPARC Antibody [OSTN/3758].

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Figure 2: Immunohistochemistry - Anti-SPARC Antibody [OSTN/3758] (A277807)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human tonsil tissue using Anti-SPARC Antibody [OSTN/3758].

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Figure 3: Immunohistochemistry - Anti-SPARC Antibody [OSTN/3758] (A277807)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human spleen tissue using Anti-SPARC Antibody [OSTN/3758].

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Figure 4: Anti-SPARC Antibody [OSTN/3758] (A277807)

Analysis of protein array containing more than 19,000 full-length human proteins using Anti-SPARC Antibody [OSTN/3758]. Z-Score and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt^TM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt^TM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target; a MAb is considered to be specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.