Synthétique Nanodisc Humain CCR8 Protéine (A318461)

Name: Synthetic Nanodisc Human CCR8 Protein
Brand: Antibodies.com
SKU: A318461
Price: 1300.0 USD
Availability: InStock

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$1,300

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Livraison

Frais de livraison

$40

Date de livraison

Livraison sous 7-8 jours ouvrables.

Nous ContacterContact

Téléphone

+1 (314) 370-6046

E-mail

orders@antibodies.com

Garanties

Qualité 100 % Garantie

Garantie de Correspondance des Prix

Spécifications

Nom du produit

Synthetic Nanodisc Human CCR8 Protein

Description du produit

Synthetic nanodiscs offer a stable and biologically relevant environment that closely mimics cell membranes and enables full-length transmembrane human CCR8 protein to be purified and analysed in vitro.

Applications

Western Blot, ELISA, SDS-PAGE

Système d'expression

HEK293 cells

Nature

Synthetic

Espèces de protéines

Human

Longueur des protéines

Full length protein.

Masse moléculaire

Full length human CCR8 protein has a MW of 40.7 kDa.

Conjuguer

Unconjugated

Forme du produit

Lyophilized

Concentration

Reconstitution dependent.

Formulation

Lyophilized from nanodisc solubilization buffer (20mM Tris-HCl, 150mM NaCl, pH 8.0). Normally 5%–8% Trehalose is added as a protectant before lyophilization.

Stockage

Shipped at 4°C. Lyophilized: Store at -20°C to -80°C. Reconstituted: Aliquot and store at -80°C. Product is stable for one year. Avoid freeze/thaw cycles.

Synonymes

C C chemokine receptor type 8, C C CKR 8, C C motif chemokine receptor 8, C-C chemokine receptor type 8, C-C CKR-8, CC chemokine receptor 8, CC chemokine receptor CHEMR1, CC chemokine receptor type 8, CC CKR 8, CC-CKR-8, CCR 8, CCR-8, CCR8 protein, CCR8-L, CCR8_HUMAN, CDw198, CDw198 antigen, Chemokine (C C motif) receptor 8, Chemokine (C C) receptor 8, Chemokine (C C) receptor like 2, Chemokine (CC motif) receptor 8, Chemokine (CC) receptor 8, Chemokine (CC) receptor like 1, Chemokine (CC) receptor like 2, Chemokine C C motif receptor 8, Chemokine C C receptor 8, Chemokine CC motif receptor 8, Chemokine CC receptor 8, Chemokine receptor 8, Chemokine receptor like 1, Chemokine receptor-like 1, CKR L1, CKR-L1, CKRL 1, CKRL1, CMKBR 8, CMKBR L2, CMKBR8, CMKBRL 2, CMKBRL2, CY 6, CY6, GPR CY6, GPR-CY6, GPRCY6, MGC123958, MGC123959, MGC129966, MGC129973, TER 1, TER1

Avertissement

Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Images (4)

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Figure 1: Synthetic Nanodisc Human CCR8 Protein (A318461)

ELISA plates were pre-coated with Synthetic Nanodisc Human CCR8 Protein (A318461) (0.2 µg/well). Serial diluted Anti-CCR8 Humanized Antibody [BMS 986340] - Azide free (A318852) solutions were added, washed, and incubated with secondary antibody before ELISA reading. From this data, the EC50 for Anti-CCR8 Monoclonal Antibody binding with CCR8-Nanodisc is 12.07 µg/ml.

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Figure 2: Western Blot - Synthetic Nanodisc Human CCR8 Protein (A318461)

Western blot analysis of Synthetic Nanodisc Human CCR8 Protein (A318461) with Anti-CCR8 Humanized Antibody [BMS 986340] - Azide free (A318852) at 1 µg/ml, followed by Goat Anti-Human IgG Antibody (HRP) at 1:5,000 dilution.

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Figure 3: Synthetic Nanodisc Human CCR8 Protein (A318461)

Synthetic Nanodisc Human CCR8 Protein (A318461) can bind Anti-CCR8 Humanized Antibody [BMS 986340] - Azide free (A318852) with an affinity constant of 1.408 nM as determined in a SPR assay.

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Figure 4: Synthetic Nanodisc Human CCR8 Protein (A318461)

Diagram showing how synthetic nanodiscs containing full-length multi-pass transmembrane proteins in a phospholipid bilayer are generated from native cell membranes.