Anti-TLR4 Anticorps [HTA125] (A280665)

$340

Anticorps monoclonal [HTA125] de souris contre TLR4 pour Flow Cytometry et IP.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-TLR4 Antibody [HTA125]
Description du produit
Mouse monoclonal [HTA125] antibody to TLR4.
Spécificité
This antibody recognises the human Toll like receptor 4 (TLR4) cell surface antigen.TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule.TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.This antibody has been demonstrated to block activation of monocytes with LPS. The use of a preservative free format of Mouse anti Human CD284 antibody, clone HTA125 (MCA2061EL ) is recommended for functional assays.
Applications
Flow Cytometry, IP
Recommander des dilutions
Flow Cytometry: 1:10 - 1:50 Pack Size: 0.1 mg 1:25 Pack Size: 0.2 mg, Use 10µl of the suggested working dilution to label 106 cells or 100µl whole blood
Reactivité
Human, Rhesus Monkey, Guinea Pig, Pig, Dog, Bovine
Immunogène
Ba/F3 cell line expressing TLR4 (CD284).
Hôte
Mouse
Clonalité
Monoclonal
Clone
HTA125
Isotype
IgG2a
Conjuguer

Unconjugated

Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Forme du produit
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Stockage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
Notes générales
Mouse anti Human CD284 antibody, clone HTA125 recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. This antibody has been demonstrated to block activation of monocytes with LPS. The use of a preservative free format of Mouse anti Human CD284 antibody, clone HTA125 (MCA2061EL ) is recommended for functional assays.
Synonymes
ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4_HUMAN, TOLL, Toll like receptor 4, Toll-like receptor 4
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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