Anti-TRBP Anticorps [PCRP-TARBP2-1E5] (A250079)

Anticorps monoclonal [PCRP-TARBP2-1E5] de souris contre TRBP pour Flow Cytometry, IF et WB.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-TRBP Antibody [PCRP-TARBP2-1E5]
Description du produit
Mouse monoclonal [PCRP-TARBP2-1E5] antibody to TRBP.
Spécificité
TRBP2, also known as TARBP2 (trans-activation-responsive (HIV-1) RNA binding protein 2), TRBP1 or TRBP, is a nuclear protein that contains three DRBM (double-stranded RNA-binding) domains. TRBP binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. The third DRBM motif in the C-terminus of human TRBP2 can interact with and inhibit PKR activity, thereby increasing HIV-1 long terminal repeat (LTR) expression. In addition, TRBP2 functions as a component of a Dicer-containing complex and associates with the catalytic subunit of the RNA-induced silencing complex (RISC), namely eIF2C2. TRBP2 is essential for Dicer stability and the proper assembly of RISC. This suggests that TRBP2, in association with Dicer, plays an important role in the processing of miRNAs (microRNAs).
Applications
Flow Cytometry, IF, WB
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human TARBP2 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-TARBP2-1E5
Isotype
IgG2a
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
45 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-TRBP Antibody [PCRP-TARBP2-1E5] - BSA and Azide free (A253259).
Synonymes
LOQS, Prbp, RISC loading complex subunit TARBP2, RISC-loading complex subunit tarbp2, TAR (HIV 1) RNA binding protein 2, TAR (HIV) RNA binding protein 2, TAR (HIV) RNA-binding protein TRBP1, TAR RNA Binding Protein 2, TAR RNA-binding protein 2, tarbp2, TARBP2 RISC loading complex RNA binding subunit, Trans-activation-responsive RNA-binding protein, TRBP1, TRBP2, TRBP2_HUMAN
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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