Anti-UBE2B Anticorps [PCRP-UBE2B-1C7] (A250264)

Anticorps monoclonal [PCRP-UBE2B-1C7] de souris contre UBE2B pour Flow Cytometry et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-UBE2B Antibody [PCRP-UBE2B-1C7]
Description du produit
Mouse monoclonal [PCRP-UBE2B-1C7] antibody to UBE2B.
Spécificité
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2A (ubiquitin-conjugating enzyme E2 A) and UBE2B (ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to post replication repair of UV-damaged DNA. UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18.
Applications
Flow Cytometry, IF
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml
Reactivité
Human
Réactivité croisée
This antibody is predicted to cross react with Mouse, Rat, Xenopus, and Zebrafish.
Immunogène
Recombinant full-length human UBE2B protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-UBE2B-1C7
Isotype
IgG2b
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
17 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-UBE2B Antibody [PCRP-UBE2B-1C7] - BSA and Azide free (A253444).
Synonymes
E2 17kDa, E2 protein, hHR6B, HR6B, RAD6 homolog B, RAD6B, UBC2, UBE2B_HUMAN, Ubiquitin carrier protein B, Ubiquitin conjugating enzyme E2 B, Ubiquitin conjugating enzyme E2B, Ubiquitin conjugating enzyme E2B (RAD6 homolog), Ubiquitin protein ligase B, Ubiquitin-conjugating enzyme E2 17 kDa, Ubiquitin-conjugating enzyme E2 B, Ubiquitin-conjugating enzyme E2-17 kDa, Ubiquitin-protein ligase B
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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