Rabbit polyclonal antibody to GSK3 beta (phospho Ser9).
Specificity
This antibody recognises GSK3 beta when phosphorylated at serine 9. GSK3 is a member of the CMGC family of kinases. GSK3 comprises two isoforms, alpha and beta, with 85% total homology and 98% homology between kinase domains. GSK3 beta is phosphorylated at serine 9 by protein kinase A, AKT and ribosomal S6 kinases p90RSK and p70S6K. Phosphorylation of GSK3 beta at serine 9 leads to inactivation of GSK3 alpha.
Applications
WB
Dilutions
WB: 1:200 - 1:500
Reactivity
Human
Immunogen
Phospho-specific peptide corresponding to residues surrounding Ser9 of human GSK3 BETA.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti GSK3 Beta (pSer9) antibody recognizes GSK3 beta when phosphorylated at serine 9. GSK3 is a member of the CMGC family of kinases. GSK3 comprises two isoforms, alpha and beta, with 85% total homology and 98% homology between kinase domains. GSK3 beta is phosphorylated at serine 9 by protein kinase A, AKT and ribosomal S6 kinases p90RSK and p70S6K. Phosphorylation of GSK3 beta at serine 9 leads to inactivation of GSK3 alpha.
![Western Blot - Anti-GSK3 beta (phospho Ser9) Antibody [ARC0069] (A308989) - Antibodies.com](https://cdn.antibodies.com/image/catalog/308/A308989_1.jpg?profile=product_alternative)
![Western Blot - Anti-GSK3 beta (phospho Ser21) Antibody [ARC54771] (A308976) - Antibodies.com](https://cdn.antibodies.com/image/catalog/308/A308976_1.jpg?profile=product_alternative)
