Anti-HER2 Antibody [HRB2/451] (A248448)

Name: Anti-HER2 Antibody [HRB2/451]
Brand: Antibodies.com
SKU: A248448
Price: 525.0 USD
Availability: InStock

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$525

Mouse monoclonal [HRB2/451] antibody to HER2 for ELISA, Flow Cytometry and IF.

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Delivery

Freight Charges

$40 to United States

Lead Time

4-6 Business Days

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Monospecific Antibody Endosomal Marker

Specifications

Name

Anti-HER2 Antibody [HRB2/451]

Description

Mouse monoclonal [HRB2/451] antibody to HER2.

Specificity

This antibody is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

Applications

ELISA, Flow Cytometry, IF

Dilutions

Flow Cytometry: 1-2 µg/million cells, IF: 1-4 µg/ml

Reactivity

Human

Immunogen

Recombinant human HER2 protein.

Host

Mouse

Clonality

Monoclonal

Clone ID

HRB2/451

Isotype

IgG1

Light Chains

kappa

Conjugate

Unconjugated

Purification

Protein A/G chromatography.

Concentration

200 µg/ml

Molecular Weight

185 kDa

Product Form

Liquid

Formulation

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Notes

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HER2 Antibody [HRB2/451] - BSA and Azide free (A251630).

Synonyms

C erb B2/neu protein, CD340, CD340 antigen, Cerb B2/neu protein, CerbB2, Erb b2 receptor tyrosine kinase 2, ErbB 2, ERBB2, ERBB2_HUMAN, HER 2, HER 2/NEU, Herstatin, Human epidermal growth factor receptor 2, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEU, NEU proto oncogene, Neuro/glioblastoma derived oncogene homolog, Neuroblastoma/glioblastoma derived oncogene homolog, NGL, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, Receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase type cell surface receptor HER2, Tyrosine kinase-type cell surface receptor HER2, V erb b2 avian erythroblastic leukemia viral oncogene homolog 2, V erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog), V erb b2 avian erythroblastic leukemia viral oncoprotein 2, V erb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog, V erb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog, Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Isotype Controls

Suitable Secondaries

See all Anti-Mouse IgG Secondaries →

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation Data (6)

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Figure 1: Immunofluorescence - Anti-HER2 Antibody [HRB2/451] (A248448)

Immunofluorescent analysis of methanol fixed MCF-7 cells stained with Anti-HER2 Antibody [HRB2/451] followed by Goat Anti-Mouse IgG (CF® 488) (Green). Nuclear counterstain is RedDot.

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Figure 2: Flow Cytometry - Anti-HER2 Antibody [HRB2/451] (A248448)

Flow cytometric analysis of human trypsinized MCF-7 cells using Anti-HER2 Antibody [HRB2/451] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Isotype Control (Red).

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Figure 3: SDS-PAGE - Anti-HER2 Antibody [HRB2/451] (A248448)

SDS-PAGE analysis of Anti-HER2 Antibody [HRB2/451] under non-reduced and reduced conditions; showing intact IgG and intact heavy and light chains, respectively. SDS-PAGE analysis confirms the integrity and purity of the antibody.

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Figure 4: Flow Cytometry - Anti-HER2 Antibody [HRB2/451] (A248448)

Flow cytometric analysis of human trypsinized SK-BR3 cells using Anti-HER2 Antibody [HRB2/451] followed by Goat Anti-Mouse IgG (CF® 488) (Blue). Isotype Control (Red).