Recombinant Anti-NeuN Antibody [NeuN/288R] (A277965)

Recombinant rabbit monoclonal [NeuN/288R] antibody to NeuN for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Freight Charges
Lead Time
4-6 Business Days
Telephone
+1 (314) 370-6046
Mon - Fri, 8am - 4pm AST
Email
orders@antibodies.com

Highlighted products for Anti-NeuN Antibody

Name
Anti-NeuN Antibody [NeuN/288R]
Description
Recombinant rabbit monoclonal [NeuN/288R] antibody to NeuN.
Specificity
NeuN antibody specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei and some proximal neuronal processes in both fetal and adult brain although, some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are examples. Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuro. Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5. Strong nuclear staining suggests a nuclear regulatory protein function; however, no evidence currently exists as to whether the NeuN protein antigen has a function in the distal cytoplasm or whether it is merely synthesized there before being transported back into the nucleus. No difference between protein isolated from purified nuclei and whole brain extract on immunoblots has been found.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human, Mouse
Immunogen
Recombinant full-length human NeuN protein.
Host
Rabbit
Clonality
Monoclonal
Clone ID
NeuN/288R
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
48 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NeuN Antibody [NeuN/288R] - BSA and Azide free (A278553).
Synonyms
FLJ56884, FLJ58356, Fox-1 homolog C, fox1 homolog C, Fox3, FOX3NeuN, hexaribonucleotide binding protein 3, HRNBP3, neuronal nuclei, Rbfox3, RFOX3_HUMAN, RNA binding protein fox-1 homolog 3, RNA binding protein, fox 1 homolog (C. elegans) 3
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
Publishing research using Recombinant Anti-NeuN Antibody [NeuN/288R] (A277965)? Please let us know so that we can list the citation on this page.

Alternative products to Anti-NeuN Antibody [NeuN/288R] (A277965)

Top