IL2 ist ein Gen, das durch das Symbol IL2 kodiert wird. Im Allgemeinen auch bezeichnet als: Interleukin-2; IL-2; T-cell growth factor; TCGF. IL2 hat eine Masse von 17.63kDa und eine Aminosäurelänge von 153.
Wir bieten 78 antikörper gegen IL2, aufgewachsen in Kaninchen, Maus, Ratte und Huhn, welche geeignet sind für WB, IHC, ELISA, ICC/IF, FC and IP mit Proben abgeleitet von Human, Maus, Ratte, Rind, Schwein, Kaninchen, Schaf, Huhn, Hund, Frettchen und Primaten.
Gen- und Proteininformationen
UniProt Zusammenfassung
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
Entrez Zusammenfassung
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Sequenzähnlichkeiten
Belongs to the IL-2 family.
