Anti-Annexin A1 Anticorps [ANXA1/3566] (A251997)

Nom du produit
Anti-Annexin A1 Antibody [ANXA1/3566] - BSA and Azide free
Description du produit
Mouse monoclonal [ANXA1/3566] antibody to Annexin A1.
Spécificité
The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.
Applications
Flow Cytometry, IF, WB, IHC-P
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human Annexin A1 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
ANXA1/3566
Isotype
IgG2a
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
38 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Annexin A1 Antibody [ANXA1/3566] (A248817).
Synonymes
Annexin 1, Annexin I, Annexin I (lipocortin I), Annexin-1, AnnexinA1, AnnexinI, ANX 1, ANX A1, ANX1, ANXA 1, ANXA1, ANXA1 protein, ANXA1_HUMAN, Calpactin 2, Calpactin II, Calpactin-2, CalpactinII, Chromobindin 9, Chromobindin-9, Chromobindin9, HGNC:533, Lipocortin 1, Lipocortin I, Lipocortin1, LipocortinI, LPC 1, LPC1, p35, Phospholipase A2 inhibitory protein
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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