Anti-CREB5 Anticorps [PCRP-CREB5-1G8] (A250809)

Anticorps monoclonal [PCRP-CREB5-1G8] de souris contre CREB5 pour Flow Cytometry, IF et WB.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-CREB5 Antibody [PCRP-CREB5-1G8]
Description du produit
Mouse monoclonal [PCRP-CREB5-1G8] antibody to CREB5.
Spécificité
The ATF/CREB family consists of a series of transcription factors that function by binding to the cAMP responsive element (CRE) palindromic octanucleotide, TGACCTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB-3 and Luman), CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. These transcription factors share terminal leucine zipper dimerization and basic DNA binding domains and are highly variable in their N-termini. Although each of the ATF/ CREB proteins bind CREs in their homodimeric form, they can also bind as heterodimers, both within the ATF/CREB family and with members of the AP-1 transcription factor family. Protein kinase A- mediated CREB phosphorylation induces association with a nuclear protein designated CBP (CREB-binding protein), which may represent a CREB coactivator. CRE-BPa is a nuclear protein that binds DNA as a homodimer but can also form a heterodimer with ATF-2 or Jun.
Applications
Flow Cytometry, IF, WB
Recommander des dilutions
Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml
Reactivité
Human
Réactivité croisée
This antibody is predicted to cross react with Mouse and Rat.
Immunogène
Recombinant full-length human CREB5 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-CREB5-1G8
Isotype
IgG2b
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Masse moléculaire
57 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-CREB5 Antibody [PCRP-CREB5-1G8] - BSA and Azide free (A253989).
Synonymes
cAMP response element binding protein 5, cAMP response element binding protein CRE Bpa, cAMP response element-binding protein CREBPa, cAMP responsive element binding protein 5, cAMP responsive element binding protein 5 isoform alpha, cAMP-responsive element-binding protein 5, CRE BPA, CRE-BPa, CREB 5, CREB-5, CREB5_HUMAN, CREBPA, cyclic AMP responsive element binding protein 5, Cyclic AMP-responsive element-binding protein 5
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

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