Anti-IRF3 Anticorps [PCRP-IRF3-3B2] (A278458)

Anticorps monoclonal [PCRP-IRF3-3B2] de souris contre IRF3 pour WB et IF.

Alternative Formats and ConjugatesAlternative Formats

Frais de livraison
Date de livraison
Livraison sous 4-6 jours ouvrables.
Téléphone
+1 (314) 370-6046
Lun - Ven, 8h - 16h AST
E-mail
orders@antibodies.com
Nom du produit
Anti-IRF3 Antibody [PCRP-IRF3-3B2] - BSA and Azide free
Description du produit
Mouse monoclonal [PCRP-IRF3-3B2] antibody to IRF3.
Spécificité
Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-αand β) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-αand interferon-βgenes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3γp48 and IFN consensus sequence-binding protein (ICSBP).
Applications
WB, IF
Recommander des dilutions
WB: 2-4 µg/ml, IF: 1-2 µg/ml
Reactivité
Human
Immunogène
Recombinant full-length human IRF3 protein.
Hôte
Mouse
Clonalité
Monoclonal
Clone
PCRP-IRF3-3B2
Isotype
IgG1
Chaînes légères
kappa
Conjuguer

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Masse moléculaire
50 kDa
Forme du produit
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Stockage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Notes générales
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-IRF3 Antibody [PCRP-IRF3-3B2] (A277870).
Synonymes
IIAE7, Interferon regulatory factor 3, IRF 3, IRF-3, IRF3_HUMAN, MGC94729
Avertissement
Ce produit est uniquement destiné à la recherche. Il n'est pas destiné à un usage diagnostique ou thérapeutique.

Produits alternatifs à Anti-IRF3 Anticorps [PCRP-IRF3-3B2] (A278458)

Haut