Anti-Nestin Antibody (A283196)

Anti-Nestin Antibody

Rabbit polyclonal antibody to Nestin.

This antibody recognises human Nestin, an intermediate filament involved in cytoskeletal organisation.Nestin is a marker of multipotent neuroectodermal cells and is downregulated as the cells cease division and differentiate to their neural or glial lineages.Expression of Nestin is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinomas.

WB, IHC-P, ELISA

ELISA: 1:20,000 - 1:80,000, IHC-P: 5 µg/ml, WB: 1:500 - 1:3,000

Human, Macaque, Mouse, Bovine, Dog, Hamster, Rat, Rabbit

Recombinant human Nestin (amino acids 1484-1500).

PILTDAHELQPQAEGIQ

Rabbit

Polyclonal

IgG

500 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human nestin antibody recognizes human Nestin, an intermediate filament involved in cytoskeletal organisation.Nestin is a marker of multipotent neuroectodermal cells and is downregulated as the cells cease division and differentiate to their neural or glial lineages. Expression of Nestin is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinomas.

ESTM 46, FLJ 21841, FLJ21841, Intermediate filament protein, Nbla00170, nes, NEST_HUMAN