Mesenchymal stem cells (MSCs) are a type of multipotent adult stem cell that can differentiate into various cell types, including bone, cartilage, and fat cells. In the context of research and clinical applications, there are several common negative markers used to characterize and identify MSCs negative for such markers. These markers are typically expressed at low or undetectable levels in MSCs, helping to distinguish them from other cell types. Some of the commonly used negative markers for MSCs include: 1) CD45 (Cluster of Differentiation 45): CD45 is a marker for hematopoietic cells, including white blood cells (leukocytes). MSCs are typically negative for CD45 expression; 2) CD34: CD34 is a marker associated with hematopoietic stem and progenitor cells. MSCs are generally negative for CD34; 3) CD14: CD14 is a marker for monocytes and macrophages. MSCs are typically negative for CD14; 4) CD31: CD31 is a marker for endothelial cells. MSCs are generally negative for CD31 expression; 5) CD11b: CD11b is a marker for myeloid lineage cells, including macrophages and granulocytes. MSCs are typically negative for CD11b; 6) CD19: CD19 is a marker for B cells. MSCs are generally negative for CD19 expression; 7) CD3: CD3 is a marker for T cells. MSCs are typically negative for CD3; 8) CD79a: CD79a is a marker for B cells. MSCs are generally negative for CD79a; 9) CD235a (Glycophorin A): CD235a is a marker for erythroid lineage cells. MSCs are usually negative for CD235a expression; 10) CD14: a glycosylphosphatidylinositol (GPI)-anchored cell surface protein that primarily acts as a co-receptor for the recognition of lipopolysaccharide (LPS), a component of the cell walls of Gram-negative bacteria. CD14 is expressed on various immune cells and other cell types involved in the innate immune response. It's important to note that whilst these markers are commonly used to identify MSCs by their lack of expression, the absence of these markers alone is not sufficient to definitively characterize MSCs. Researchers often use a combination of positive markers (e.g., CD73, CD90, CD105) and negative markers to more accurately identify and isolate MSCs from other cell types. Additionally, the specific markers used for MSC identification may vary depending on the source of the cells (e.g., bone marrow, adipose tissue, umbilical cord). We provide a wide product range of research reagents for investigating MSCs negative markers, including CD34 antibodies, CD14 antibodies, CD11b antibodies, CD11b ELISA Kits, and CD14 ELISA Kits. Explore our full MSCs negative markers product range below and discover more, for less.