Anti-NF-L Antibody [SPM204] (A249495)

Anti-NF-L Antibody [SPM204]

Mouse monoclonal [SPM204] antibody to NF-L.

This antibody reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

IF, IHC-P

IF: 1-2 µg/ml, Flow Cytometry: 1-2 µg/million cells, IHC-P: 1-2 µg/ml

Human, Rat, Porcine, Bovine, Chicken

Native neurofilament purified from human brain.

Mouse

Monoclonal

SPM204

IgG1

kappa

Protein A/G chromatography.

200 µg/ml

68 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NF-L Antibody [SPM204] - BSA and Azide free (A252675).

68 kDa neurofilament protein, 68kDa Neurofilament, NEFL, Neurofilament light polypeptide, Neurofilament triplet L protein, NF68, NFL